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      我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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      您當前所在位置:首 頁 > 產品展示 > 人類 > 口腔細胞系統 人口腔角質細胞 HOK

      人口腔角質細胞 HOK

      英文名:Human Oral Keratinocytes

      貨號:2610

      價格:$738

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      ? ? ? 口腔黏膜角化細胞是口腔疾病主要屏障,保護局部細胞免受微生物和化學物質造成的傷害。它們通過不斷產生或受刺激后產生的細胞因子,刺激參與促發炎癥反應,這意味著它們可能通過炎癥過程潛在地參與口腔感染的調控,該過程需要不同的白細胞介素參與,如IL-1?和IL-18??谇火つそ腔毎磉_多種不同的細胞標志物,該表達受到目標基因轉錄過程中鈣素誘導變化的影響??谇火つそ腔毎c特征明顯的皮膚角質細胞在結構和功能上有很大的相似性,并且為研究角質細胞的生物學特性、無限增殖過程、惡性轉化提供了良好的模型。


      ? ? ? ScienCell人口腔黏膜角化細胞提取于人口腔黏膜,一代凍存。每管含有細胞數>5×105 cells/ml,此細胞通過Cytokeratine-8, -18 and -19免疫熒光染色驗證,經測試不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌。細胞可以達到10倍增。

      推薦培養基:口腔角質細胞培養基 (OKM, Cat. #2611)

      貨號2610
      產地美國
      縮寫HOK
      規格5 x 10^5 /1ml
      用途科研
      儲存液氮
      運輸干冰
      1.) Yen YC, Shiah SG, Chu HC, Hsu YM, Hsiao JR, Chang JY, Hugn WC, Liao CT, Cheng AJ, Lu YC, Chen YW. (2014) 'Reciprocal regulation of MicroRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells.'?Mol cancer.

      2.) Yen YC, Shiah SG, Chu HC, Hsu YM, Hsiao JR, Chang JY, Hugn WC, Liao CT, Cheng AJ, Lu YC, Chen YW. (2014) "Reciprocal regulation of MicroRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells."?Mol cancer. 13: 6.

      3.) Ji W, Lee C, Chen JY, Cheng Y, Yang S, Chen J, Chen H. (2013) "Areca Nut Extract Induces Pyknotic Necrosis in Serum-Starved Oral Cells via Increasing Reactive Oxygen Species and Inhibiting GSK3: An Implication for Cytopathic Effects in Betel Quid Chewers."?PLoS One. 8: e63295.

      4.) Wallet MA, Calderon NL, Alonso TR, Choe CS, Catalfamo DL, Lalane CJ, Naiva KG, Panagakos F, Wallet SM. (2013) ?Triclosan alters antimicrobial and inflammatory responses of epithelial cells.??Oral dis.?19: 296-302.

      5.) Talwar S, Balasubramanian S, Sundaramurthy S, House R, Wilusz CJ, Kuppuswamy D, D'Silva N, Gillespie MB, Hill EG, Palanisamy V. (2013) "Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells."?RNA Biol. 10: 277-86.

      6.) Lee SS, Tsai CH, Yu CC, Chang YC. (2013) "Elevated Snail Expression Mediates Tumor Progression in Areca Quid Chewing-Associated Oral Squamous Cell Carcinoma via Reactive Oxygen Species."?PLoS One. 8: e67985.

      7.) Kim JS, Yu SK, Lee MH, Park MG, Park E, Kim SG, Lee SY, Kim CS, Kim HJ, Chun HS, Chun SW, Kim DK. (2013) 'MicroRNA-205 directly regulates the tumor suppressor, interleukin-24, in human KB oral cancer cells.'

      8.) Kim JS, Yu SK, Lee MH, Park MG, Park E, Kim SG, Lee SY, Kim CS, Kim HJ, Chun HS, Chun SW, Kim DK. (2013) "MicroRNA-205 directly regulates the tumor suppressor, interleukin-24, in human KB oral cancer cells."?Mol cells. 35: 17-24.

      9.) Russo N, Wang X, Liu M, Banerjee R, Goto M, Scanlon C, Metwally t, Inglehart RC, Tsodikov A, Duffy S, Tubergen EV, Bradford C, Carey T, Wolf G, Chinnaiyan AM, D

      10.) Kumar B, Yadav A, Lang JC, Cipolla MJ, Schmitt AC, Arradaza N, Teknos TN, Kumar P. (2012) 'YM155 reverses cisplatin resistance in head and neck cancer by decreasing cytoplasmic survivin levels.'

      11.) Kumar B, Yadav A, Lang JC, Cipolla MJ, Schmitt AC, Arradaza N, Teknos TN, Kumar P. (2012) "YM155 reverses cisplatin resistance in head and neck cancer by decreasing cytoplasmic survivin levels."?Mol cancer ther.?11: 1988-98.

      12.) Van Tubergen E, Vander Broek R, Lee J, Wolf G, Carey T, Bradford C, Prince M, Kirkwood KL, D'Silva NJ. (2011) "Tristetraprolin regulates interleukin-6, which is correlated with tumor progression in patients with head and neck squamous cell carcinoma."?Cancer. 117: 2677-89.

      13.) Jiang L, Liu X, Kolokythas A, Yu J, Wang A, Heidbreder CE, Shi F, Zhou X. (2010) "Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma."?Int J Cancer. 127: 505-12.

      14.) Mitchell C, Joyce AR, Piper JT, McKallip RJ, Fariss MW. (2010) "Role of oxidative stress and MAPK signaling in reference moist smokeless tobacco-induced HOK-16B cell death."?Toxicol Lett. 195: 23-30.

      15.) Phan TC, Ooi J, Goonewardene MS. (2010) "A novel molecule, SLURP-1, enhances the survival of periodontal ligament fibroblasts."?J Periodontal Res. 45: 331-6.?

      16.) Rao SK, Pavicevic Z, Du Z, Kim JG, Fan M, Jiao Y, Rosebush M, Samant S, Gu W, Pfeffer LM, Nosrat CA. (2010) "Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma."?J Biol Chem. 285: 32512-21.

      17.) Dowejko A, Bauer RJ, M?ller-Richter UD, Reichert TE. (2009) "The human homolog of the Drosophila headcase protein slows down cell division of head and neck cancer cells."?Carcinogenesis. 30: 1678-85.

      18.) Ghosh A, Park JY, Fenno C, Kapila YL. (2008) "Porphyromonas gingivalis, gamma interferon, and a proapoptotic fibronectin matrix form a synergistic trio that induces c-Jun N-terminal kinase 1-mediated nitric oxide generation and cell death."?Infect Immun. 76: 5514-23.

      19.) M?ller-Richter UD, Dowejko A, Zhou W, Reichert TE, Driemel O. (2008) "Different expression of MAGE-A-antigens in foetal and adult keratinocyte cell lines."?Oral Oncol. 44: 628-33.?

      20.) Liang SC, Tan XY, Luxenberg DP, Karim R, Dunussi-Joannopoulos K, Collins M, Fouser LA. (2006) "Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides."?J Exp Med. 203: 2271-9.

      Question:

      I use poly-L-lysine to coat my plate to culture HOK(Human Oral Keratinocytes) cells. I also found out that we have poly-D-lysine. Can I use poly-D-lysine to coat my plate and culture HOK or other primary cells?

      Answers:

      Thanks for asking! Although we have not tested it, poly-D-lysine should work for these cells.
      ?
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      99久久香蕉国产线看观看

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