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      我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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      您當前所在位置:首 頁 > 產品展示 > 人類 > 視覺細胞系統 人小梁網細胞 HTMC

      人小梁網細胞 HTMC

      英文名:Human Trabecular Meshwork Cells

      貨號:6590

      價格:$754

      產品說明書下載:

      產品預訂,提交訂單信息之后,我們會第一時間與您取得聯系!
      小梁網位于虹膜底部周圍,并有一個開口進入鞏膜靜脈竇,將廢棄物質傳輸至靜脈血管。小梁網細胞在房水的流出中起重要作用,且這條路徑是眼壓依賴的。小梁網細胞的損傷和死亡與開角青光眼的發病有關。小梁網細胞進一步的表達神經遞質和神經肽受體,受極低濃度的血管活性多肽和生長因子調節,使這些細胞對小梁網的多層次滲透。體外培養TMC是研究小梁網調節功能的良好模型,并對青光眼治療技術的開發非常有幫助。
      Sciencel的原代凍存,冰凍運輸。每管細胞密度超過5×10^5/ml。細胞特性經α-平滑肌肌動蛋白和纖維粘連蛋白免疫熒光鑒定。本細胞經檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。如采用ScienCell實驗室提供的實驗條件,可保證此細胞15倍增增殖。


      推薦培養基:小梁網細胞培養基 (TMCM, Cat. #6591)
      貨號6590
      產地美國
      縮寫HTMC
      規格5 x 10^5 /1ml
      用途科研
      儲存液氮
      運輸干冰
      1.) Diskin S, Chen WS, Cao Z, Gyawali S, Gong H, Soza A, Gonz?lez A, Panjwani N. (2012) "Galectin-8 promotes cytoskeletal rearrangement in trabecular meshwork cells through activation of Rho signaling." PLoS One. 7: e44400.

      2.) Famili A, Ammar DA, Kahook MY. (2013) "Ethyl pyruvate treatment mitigates oxidative stress damage in cultured trabecular meshwork cells." Mol Vis. 19: 1304-9.

      3.) Sacc? SC, La Maestra S, Micale RT, Larghero P, Travaini G, Baluce B, Izzotti A. (2011) "Ability of dorzolamide hydrochloride and timolol maleate to target mitochondria in glaucoma therapy." Arch Ophthalmol. 129: 48-55.

      4.) Miyamoto N, Izumi H, Miyamoto R, Kondo H, Tawara A, Sasaguri Y, Kohno K. (2011) "Quercetin induces the expression of peroxiredoxins 3 and 5 via the Nrf2/NRF1 transcription pathway." Invest Ophthalmol Vis Sci. 52: 1055-63.

      5.) Hudson BD, H?bert TE, Kelly ME. (2010) "Physical and functional interaction between CB1 cannabinoid receptors and beta2-adrenoceptors." Br J Pharmacol. 160: 627-42.

      ?

      Question:

      Hello. I would like to know how long the human trabecular meshwaork cells survive in culture? For example, 20 passages or 15 doublings? Thank you


      ? Answers:

      • Dear?Mijin,

        According to the?product sheet, we guarantee 15 population doublings for this cell. Thanks!

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      99久久香蕉国产线看观看

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