乳腺上皮細胞(HMEpiC)位于乳腺小葉的泡狀腺,配合乳腺管和脂肪組織,形成一個復雜的乳腺系統。MEpiC受各種生長因子和激素信號影響,并在產前產后、青春期、孕期經歷生長、侵襲和分化等過程。激素分泌、細胞外基質成分異常和其他遺傳因素會引起MEpiC的增殖失控,導致乳腺癌的發展。了解MEpiC的特性將有助于我們研究乳腺癌疾病的發病機理和新的治療靶標。
ScienCell實驗室的HMEpiC分離自人乳腺,原代凍存,冰凍運輸。每管細胞密度超過5×10^5/ml。細胞經Cyt-14,-18,-19的免疫熒光鑒定。本細胞經檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。如采用ScienCell?實驗室特制的培養基,可保證此細胞15次或以上的倍增。
推薦培養基:乳腺上皮細胞培養基 (MEpiCM, Cat. #7611)
貨號 | 7610 |
產地 | 美國 |
縮寫 | HMEpiC |
規格 | 5 x 10^5 /1ml |
用途 | 科研 |
儲存 | 液氮 |
運輸 | 干冰 |
1.) Zhang L, Webster TJ. (2013) "Effects of chemically modified nanostructured PLGA on functioning of lung and breast cancer cells."?Int J Nanomedicine. 8: 1907-19.
2.) Lu RM, Chen MS, Chang DK, Chiu CY, Lin WC, Yan SL, Wang YP, Kuo YS, Yeh CY, Lo A, Wu HC. (2013) "Targeted drug delivery systems mediated by a novel Peptide in breast cancer therapy and imaging."?PLoS One. 8: e66128.?
3.) Fong C, Weerawardena A, Sagnella SM, Mulet X, Krodkiewska I, Chong J, Drummond CJ. (2011) "Monodisperse Nonionic Isoprenoid-Type Hexahydrofarnesyl Ethylene Oxide Surfactants: High Throughput Lyotropic Liquid Crystalline Phase Determination."?Langmuir.?
4.) Gong X, Moghaddam MJ, Sagnella SM, Conn CE, Danon SJ, Waddington LJ, Drummond CJ. (2011) "Lamellar crystalline self-assembly behaviour and solid lipid nanoparticles of a palmityl prodrug analogue of Capecitabine-A chemotherapy agent."?Colloids Surf B Biointerfaces. 85: 349-59.
5.) Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, Wei M, Madia F, Cheng CW, Hwang D, Martin-Montalvo A, Saavedra J, Ingles S, de Cabo R, Cohen P, Longo VD. (2011) "Growth hormone receptor deficiency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans."?Sci Transl Med. 3: 70ra13.?
6.) Sagnella SM, Conn CE, Krodkiewska I, Moghaddam M, Drummond CJ. (2010) "Endogenous nonionic saturated monoethanolamide lipids: solid state, lyotropic liquid crystalline, and solid lipid nanoparticle dispersion behavior."?J Phys Chem B. 114: 1729-37.
7.) Huang Y, Song N, Ding Y, Yuan S, Li X, Cai H, Shi H, Luo Y. (2009) "Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis."?Cancer Res. 69: 7529-37.
There are no product questions yet.