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中國區首家總代 專業十六載 打造細胞生物學精品
英文名：Human Hair Outer Root Sheath Cells
貨號：2420
價格：$726
產品說明書下載： 
? ? ? 人毛囊外根鞘細胞位于毛球基部的乳頭周圍，屬于再生細胞范疇。它是毛發生長和毛發中黑色素轉運的主要來源。在毛發生長的活躍階段，基質中的細胞快速增長和分化導致毛發增長。生發基質細胞經歷被稱為角質化的過程，形成一層角蛋白以抑制毛發脫落。毛囊具有基質細胞的免疫特權。濾泡細胞培植研究表明生發基質細胞能通過植入毛乳頭細胞來誘導新毛囊形成。
| 貨號 | 2420 |
| 產地 | 美國 |
| 縮寫 | HHORSC |
| 規格 | 5 x 10^5 /1ml |
| 用途 | 科研 |
| 儲存 | 液氮 |
| 運輸 | 干冰 |
Hi, I'm interested on acquiring an Outer Root Sheath (ORS) cell line, however I can't understand why you say these cells have mesenchymal morphology and stain against CD105. These are markers of mesenchymal cells but Outer Root Sheath (ORS) cells are epithelial cells! They should not stain for markers of mesenchymal cells. The mesenchymal cells present in the hair follicle are dermal papilla and dermal sheath cells, not ORS cells! ORS are extremely different cells, they have to interact with mesenchymal cells, but they have a very different origin and function in the hair follicle. I want to buy a cell line that represents this. If you say your cell line stains for mesenchymal markers, your characterization of the cell line tells me that probably it is not a pure cell line and that you must certainly have a mixture of ORS cells and mesenchymal cells, like dermal sheath cells, since these mesenchymal cells surround ORS cells in the hair follicle That assumption is also present when you say the optimal medium is a mesenchymal stem cell medium. Most certainly a mesenchymal stem cell medium is not the optimal medium to culture epithelial cells. I need a pure cell line of ORS cell to compare to another epithelial population I have, otherwise I would be spending money in a wrong comparison because I would be using a cell line with a heterogeneous population of epithelial and mesenchymal cells. Please is there anyone that can give a clear answer to these questions? Someone directly involved in the isolation process of this cell line? It would be really important. I only have until next Tuesday to find and buy the cell line I need because after that the University financial department will prevent me from doing orders until next February. I would really appreciate your help. Best regards, Carla Abreu
Hi Carla,
These cells are not a cell line, they are a mixed population of primary cells isolated directly from the outer root sheath of the hair follicle and cryopreserved at passage 0. I have attached the product sheet for these cells which describes them in greater detail. Please let me know if you have additional questions about these cells after reviewing the product sheet.?
Thanks & Regards,
Manoj Sharma
