? ? ? 人黑色素細胞是神經嵴衍生細胞,位于人的某些器官,如皮膚、眼睛、內耳和軟腦膜。黑色素細胞不能向這些器官的移動,可以解釋先天性皮膚白斑(斑駁病)跟虹膜異色(不同顏色并置)之間的關系以及Waardenburg綜合征的先天性耳聾。皮膚黑色素細胞合成并轉運黑色素到周圍的角質細胞,使皮膚有色素沉積以保護皮膚對抗陽光輻射。隨著新的細胞培養技術和改良的培養方法,在成功培養這類細胞在純種群時,發現了新型的黑色素細胞基因——msgl,它能編碼一種與色素沉著相關的核蛋白。
? ? ? 人表皮黑色素細胞(深色素)提取于人表皮組織,一代凍存。每管含有細胞數>5x10^5cells/ml,此細胞通過Fibronectin和NGF-receptor(p75)免疫熒光染色驗證,經測試不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌。細胞可以達到15倍增。
推薦培養基:黑色素細胞培養基 (MelM, Cat. #2201)
貨號 | 2230 |
產地 | 美國 |
縮寫 | HEM-a |
規格 | 5 x 10^5 /1ml |
用途 | 科研 |
儲存 | 液氮 |
運輸 | 干冰 |
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2.) Looi CY, Moharram B, Paydar M, Wong YL, Leong KH, Mohamad K, Arya A, Wong WF, Mustafa MR. (2013) "Induction of apoptosis in melanoma A375 cells by a chloroform fraction of Centratherum anthelminticum (L.) seeds involves NF-kappaB, p53 and Bcl-2-controlled mitochondrial signaling pathways."?BMC Complement Altern Med. 13: 166.
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Question:
I purchased a HEM-a cell in February 2014 from ScienCell. Can you supply DNA (STR) profiling of this primary cell?
Thanks.
Answers:
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Posted by Manoj Sharma on Thursday, January 7, 2016
Hello,
We do not have STR profiling. thanks for your interest
SCIENCELL