99久久香蕉国产线看观看

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        我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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        人成纖維細胞生長因子信號通路qPCR檢測試劑盒

        英文名:Human Fibroblast Growth Factor Signaling Pathway qPCR Array Kit

        貨號:GK040

        價格:$250

        產品說明書下載:

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        ScienCell's GeneQuery? Human Fibroblast Growth Factor Signaling Pathway qPCR Array Kit (GQH-FGF) is designed to facilitate gene expression profiling of 88 key genes involved in Fibroblast Growth Factor (FGF) signaling pathways. FGFs are involved in a wide variety of biological functions such as embryonic development, organogenesis, angiogenesis, tissue regeneration and wound healing. Through their binding with FGF receptors (FGFRs), FGFs activate and regulate many downstream signaling pathways, such as MAPK, JNK and STAT/NF-κB. Brief examples of how included genes may be grouped according to their functions are shown below:     

        • Secreted FGFs
          • FGF1 superfamily: FGF1, FGF2
          • FGF4 superfamily: FGF4, FGF5
          • FGF7 superfamily: FGF3, FGF7, FGF10
          • FGF8 superfamily: FGF17, FGF18
          • FGF9 superfamily: FGF9, FGF16, FGF20
        • Endocrine FGFs: FGF19, FGF23
        • Intracellular FGFs: FGF13, FGF14
        • FGF receptors: FGFR1, FGFR2, FGFR3, FGFR5
        • FGF signaling inhibitors: IL17RD, SPRY2, SPRY4, PTPN1, DUSP1, DUSP6
        • Activated downstream pathways
          • MAPK pathway: FRS2, GAB1, SOS1, PTPN11, SHC1, RAS, BRAF, MAPK1, MAPK3, MAP2K1, MAP2K2
          • PI3K/AKT pathway: AKT1, AKT2, AKT3, PI3Ks, FOXO1, FOXO3, BAD, BAX, CASP9
          • JNK pathway: MAPK8, MAPK9, MAPK14, RAC1, ATF2, MAP2K4, MAP2K6
          • STAT/NF-κB pathway: STAT1, STAT3, NFKB1, NFKB2, REL, MMP9

        GeneQuery? qPCR array kits are qPCR ready in a 96-well plate format, with each well containing one primer set that can specifically recognize and efficiently amplify a target gene's cDNA. The carefully designed primers ensure that: (i) the optimal annealing temperature in qPCR analysis is 65°C (with 2 mM Mg2+, and no DMSO); (ii) the primer set recognizes all known transcript variants of target gene, unless otherwise indicated; and (iii) only one gene is amplified. Each primer set has been validated by qPCR with melt curve analysis, and gel electrophoresis. 

        GeneQuery? Human Fibroblast Growth Factor Signaling Pathway qPCR Array Plate Layout*

        (8 controls in Bold and Italic)

         

         

        1

        2

        3

        4

        5

        6

        7

        8

        9

        10

        11

        12

        A

        AKT1

        DAG1

        FGF16

        FGF4

        FOS

        IL17RD

        MAPK14

        NFATC2

        PIK3CD

        PLCG1

        SH2B1

        β-actin

        B

        AKT2

        DUSP1

        FGF17

        FGF5

        FOXO1

        JAK2

        MAPK3

        NFATC3

        PIK3CG

        PTPN1

        SHC1

        GAPDH

        C

        AKT3

        DUSP6

        FGF18

        FGF7

        FOXO3

        KRAS

        MAPK8

        NFATC4

        PIK3R1

        PTPN11

        SOS1

        LDHA

        D

        ATF2

        ELK1

        FGF19

        FGF9

        FOXO4

        MAP2K1

        MAPK9

        NFKB1

        PIK3R2

        RAC1

        SPRY2

        NONO

        E

        BAD

        FGF1

        FGF2

        FGFR1

        FRS2

        MAP2K2

        MARCKS

        NFKB2

        PIK3R3

        RAF1

        SPRY4

        PPIH

        F

        BAX

        FGF10

        FGF20

        FGFR2

        GAB1

        MAP2K4

        MMP9

        NRAS

        PIK3R4

        REL

        SRC

        GDC

        G

        BRAF

        FGF13

        FGF23

        FGFR3

        GRB2

        MAP2K6

        NFAT5

        PIK3CA

        PIK3R5

        RELA

        STAT1

        PPC

        H

        CASP9

        FGF14

        FGF3

        FGFR5

        HRAS

        MAPK1

        NFATC1

        PIK3CB

        PIK3R6

        RELB

        STAT3

        NTC

         

        * gene selection may be updated based on new research and development

        貨號GK040
        產地美國
        縮寫GQH-FGF
        規格One 96-well plate, one 20ul reaction per well
        用途科研
        儲存4°C
        運輸膠冰
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        99久久香蕉国产线看观看

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