? ? ? 皮膚血管由多種細胞和非細胞物質組成。內皮細胞是構成皮膚血管主要細胞類型。內皮細胞不僅是血管內腔和血管外的分界,還是細胞和大分子物質擴散的選擇性屏障。皮膚微血管內皮細胞與其它內皮細胞有著同之處,也有其自身特點。如能夠活化參與多種生理過程,包括創傷愈合、止血、溫度調節和炎癥調整(白細胞運輸)。內皮細胞的結構和功能在不同的時間和空間有著不同的變化。內皮細胞通過增殖、休眠、凋亡和老化這4個基本的細胞狀態來建立皮膚微血管維持和重塑之間的動態平衡。
? ? ? 人真皮微血管內皮細胞(HDMEC)提取于人真皮組織,于第一代末期凍存。每管含有細胞數超過5×105/ml,此細胞通過vWF/Factor?VIII和CD31?(P-CAM)免疫熒光染色驗證,經測試不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌。細胞可以達到15倍增。
推薦培養基:內皮細胞培養基(ECM, Cat. #1001)
貨號 | 2000 |
產地 | 美國 |
縮寫 | sciencell |
規格 | 5 x 10^5 /1ml |
用途 | 科研 |
儲存 | 液氮 |
運輸 | 干冰 |
1.) Avril M, Tripathi AK, Brazier AJ, Andisi C, Janes JH, Soma VL, Sullivan DJ Jr, Bull PC, Stins MF, Smith JD. (2012) "A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells."?Proc Natl Acad Sci USA. 109: E1782-90.
2.) Claessens A, Adams Y, Ghumra A, Lindergard G, Buchan CC, Andisi C, Bull PC, Mok S, Gupta AP, Wang CW, Turner L, Arman M, Raza A, Bozdech Z, Rowe JA. (2012) "A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells."?Proc Natl Acad Sci USA. 109: E1772-81.?
3.) Laranjeira MS, Fernandes MH, Monteiro FJ. (2012) "Reciprocal induction of human dermal microvascular endothelial cells and humanmesenchymal stem cells: time-dependent profile in a co-culture system."?Cell Prolif. 45: 320-34.
4.) Alter A, de L s leuc L, Van Thuc N, Thai VH, Huong NT, Ba NN, Cardoso CC, Grant AV, Abel L, Moraes MO, Alca s A, Schurr E. (2010) "Genetic and functional analysis of common MRC1 exon 7 polymorphisms in leprosy susceptibility."?Hum Genet. 127: 337-48.
5.) Atkinson BT, Jasuja R, Chen VM, Nandivada P, Furie B, Furie BC. (2010) "Laser-induced endothelial cell activation supports fibrin formation."?Blood. 116: 4675-83.
6.) Hardcastle J, Kurozumi K, Dmitrieva N, Sayers MP, Ahmad S, Waterman P, Weissleder R, Chiocca EA, Kaur B. (2010) "Enhanced antitumor efficacy of vasculostatin (Vstat120) expressing oncolytic HSV-1."?Mol Ther.?18: 285-94.
7.) Shahani T, Lavend'homme R, Luttun A, Saint-Remy JM, Peerlinck K, Jacquemin M. (2010) "Activation of human endothelial cells from specific vascular beds induces the release of a FVIII storage pool."?Blood. 115: 4902-9.
8.) Song X, Luo Y. (2010) "The regulatory mechanism of Hsp90alpha secretion from endothelial cells and its role in angiogenesis during wound healing."?Biochem Biophys Res Commun. 398: 111-7.
9.) Tsuji T, Aoshiba K, Nagai A. (2010) "Alveolar cell senescence exacerbates pulmonary inflammation in patients with chronic obstructive pulmonary disease."?Respiration.80: 59-70.
10.) May JM, Qu ZC, Qiao H. (2009) "Transfer of ascorbic acid across the vascular endothelium: mechanism and self-regulation."?Am J Physiol Cell Physiol. 297: C169-78.
11.) Mikula I, Durocher S, Martasek P, Mutus B, Slama-Schwok A. (2009) "Isoform-specific differences in the nitrite reductase activity of nitric oxide synthases under hypoxia."Biochem J. 418: 673-82.
12.) Xueyong L, Shaozong C, Wangzhou L, Yuejun L, Xiaoxing L, Jing L, Yanli W, Jinqing L. (2008) "Differentiation of the pericyte in wound healing: The precursor, the process, and the role of the vascular endothelial cell."?Wound Repair Regen.?16: 346-55.
??There are no product questions yet.