99久久香蕉国产线看观看

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        我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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        您當前所在位置:首 頁 > 產品展示 > 人類 > 神經細胞系統 人小膠質細胞 HM

        人小膠質細胞 HM

        英文名:Human Microglia

        貨號:1900

        價格:$878

        產品說明書下載:

        產品預訂,提交訂單信息之后,我們會第一時間與您取得聯系!

        ? ? ? 小膠質細胞是中樞神經系統中的膠質細胞類型之一,是神經膠質細胞網絡的重要組成部分。小膠質細胞出現在大腦由發育早期向成熟階段轉化的過程中,被認為是大腦免疫監視的主要細胞。小膠質細胞也表達II類主要組織相容性復合體(MHCII),向CD4陽性T細胞呈遞抗原,并能進行Fc段介導的胞吞作用,并且與造血細胞和組織巨噬細胞分享多種抗原。在大腦發育或中樞神經系統受傷發生程序性細胞死亡后,小膠質細胞能被激活。做為大腦的巨噬細胞清除組織碎片,受損細胞或微生物。另外,有大量的證據表明,小膠質細胞參與多種的生理和病理過程,它們通過與神經元和其它膠質細胞共同作用,產生諸如生長因子、細胞因子等活性物質來完成以上功能。


        ? ? ? ScienCell實驗室的HM提取自大腦皮層,原代凍存,冰凍運輸。每管細胞密度超過1×106/ml。細胞經OX-42(CD11b/c)和F4/80免疫熒光鑒定。本細胞經檢測不含HIV-1,HBV,HCV,支原體,細菌,酵母菌和真菌。如采用ScienCell實驗室特制的培養基,可保證此細胞生長良好。HM不推薦增值培養。

        推薦培養基:小膠質細胞培養基(MM, Cat. #1901)

        貨號1900
        產地美國
        縮寫HM
        規格5 x 10^5 /1ml
        用途科研
        儲存液氮
        運輸干冰
        1.) Yi L, Xiao H, Xu M, Ye X, Hu J, Li F, Li M, Luo C, Yu S, Bian X, Feng H. (2011) "Glioma-initiating cells: A predominant role in microglia/macrophages tropism to glioma." J Neuroimmunol. 232: 75-82.

        2.) Kostianovsky AM, Maier LM, Anderson RC, Bruce JN, Anderson DE. (2008) "Astrocytic regulation of human monocytic/microglial activation." J Immunol. 181: 5425-32.

        3.) Wang X, Douglas SD, Song L, Wang YJ, Ho WZ. (2008) "Neurokinin-1 receptor antagonist (aprepitant) suppresses HIV-1 infection of microglia/macrophages." J Neuroimmune Pharmacol. 3: 257-64.

        4.) Campbell GR, Watkins JD, Singh KK, Loret EP, Spector SA. (2007) "Human Immunodeficiency Virus Type 1 Subtype C Tat Fails To Induce Intracellular Calcium Flux and Induces Reduced Tumor Necrosis Factor Production from Monocytes." J Virol. 81: 5919-28.

        5.) Sui Z, Sniderhan LF, Schifitto G, Phipps RP, Gelbard HA, Dewhurst S, Maggirwar SB. (2007) "Functional Synergy between CD40 Ligand and HIV-1 Tat Contributes to Inflammation: Implications in HIV Type 1 Dementia." J Immunol. 178: 3226-36.

        6.) Cassiani-Ingoni R, Cabral ES, L nemann JD, Garza Z, Magnus T, Gelderblom H, Munson PJ, Marques A, Martin R. (2006) "Borrelia burgdorferi induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-Class II expression." J Neuropathol Exp Neurol. 65: 540-8.
        ?

        1、Question:

        Dear whom it may concern, I’m wondering whether your microglia express chemokine receptors particularly, CD36, TLR3, TLR4, TLR7. Any finding by you or your customers are valuable for me to use your cells as the model. Thanks, H.Cho

        Answers:

        We do not test for the receptors listed. Thank you for your interest in ScienCell products

        2、Question:

        Hello, Do these human microglia immortalized cells express CD80/86 as normal microglia do when stimulated? Also, are there any publications that utilized this cell line for flow cytometryic analysis? Thanks

        Answers:

        Human microglia provided by ScienCell are primary cells, not immortalized cell lines. Thank you for your interest

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        99久久香蕉国产线看观看

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