99久久香蕉国产线看观看

<dfn id="h3pb5"><noframes id="h3pb5">

    <output id="h3pb5"></output>

      <dfn id="h3pb5"><nobr id="h3pb5"><mark id="h3pb5"></mark></nobr></dfn>

      <listing id="h3pb5"><form id="h3pb5"></form></listing>
        我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
        ?
        您當前所在位置:首 頁 > 產品展示 > 人類 > 神經細胞系統 人腦血管周細胞 HBVP

        人腦血管周細胞 HBVP

        英文名:Human Brain Vascular Pericytes

        貨號:1200

        價格:$718

        產品說明書下載:

        產品預訂,提交訂單信息之后,我們會第一時間與您取得聯系!

        ? ? ? ?周細胞是具伸縮性的平滑肌細胞樣的細胞,它們覆蓋在微脈管的基底面。周細胞是小靜脈的主要成分,并普遍存在于毛細血管中。在不同的組織和器官中,周細胞的數量和功能均呈現很大的差異。腦血管周細胞的主要功能包括參與中樞神經系統微血管收縮性,內皮細胞活性及巨噬細胞活性的調節。也有證據表明周細胞與血腦屏障的物質轉運及血管滲透性的調節有關。病理學研究顯示,周細胞與高血壓,糖尿病視網膜病變,阿爾海默氏病,多發性硬化和中樞神經系統腫瘤的形成有關。


        ? ? ? ScienCell?實驗室的HBVP分離自人大腦組織,原代凍存,冰凍運輸。每管細胞密度超過5×105/ml。細胞經α-smooth?muscle?actin免疫熒光鑒定。本細胞經檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。如采用ScienCell?實驗室特制的培養基,可保證此細胞達到15次或以上的倍增。

        推薦培養基:周細胞培養基 (PM, Cat. #1201)
        貨號1200
        產地美國
        縮寫HBVP
        規格5 x 10^5 /1ml
        用途科研
        儲存液氮
        運輸干冰
        1.) You WK, Yotsumoto F, Sakimura K, Adams RH, Stallcup WB. (2014) 'NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function.'

        2.) Santos ARC, Dvoriantchikova G, Li Y, Mohammad G, El-Asrar AMA, Wen R, Ivanov D. (2014) 'Cellular Mechanisms of High Mobility Group 1 (HMGB-1) Protein Action in the Diabetic Retinopathy.'

        3.) Lippmann ES, Al-Ahmad A, Azarin SM, Palecek SP, Shusta EV. (2014) 'A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources.'

        4.) Lippmann ES, Al-Ahmad A, Azarin SM, Palecek SP, Shusta EV. (2014) "A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources." 4.

        5.) Santos ARC, Dvoriantchikova G, Li Y, Mohammad G, El-Asrar AMA, Wen R, Ivanov D. (2014) "Cellular Mechanisms of High Mobility Group 1 (HMGB-1) Protein Action in the Diabetic Retinopathy." PLOS ONE. 9: e87574.

        6.) You WK, Yotsumoto F, Sakimura K, Adams RH, Stallcup WB. (2014) "NG2 proteoglycan promotes tumor vascularization via integrin-dependent effects on pericyte function." Angiogenesis. 17: 61-76.

        7.) Urich E, Patsch C, Aigner S, Graf M, Iacone R, Freskgrd P. (2013) "Multicellular self-assembled spheroidal model of the blood brain barrier." Sci Rep. 3: 1500.

        8.) Mandrup OA, Friis NA, Lykkemark S, Just J, Kristensen P. (2013) "A Novel Heavy Domain Antibody Library with Functionally Optimized Complementarity Determining Regions." PLoS One. 8: e76834.

        9.) Glinskii OV, Huxley VH, Glinskii VV, Rubin LJ, Glinsky VV. (2013) 'Pulsed Estrogen Therapy Prevents Post-OVX Porcine Dura Mater Microvascular Network Weakening via a PDGF-BB-Dependent Mechanism.' PloS one.

        10.) Glinskii OV, Huxley VH, Glinskii VV, Rubin LJ, Glinsky VV. (2013) "Pulsed Estrogen Therapy Prevents Post-OVX Porcine Dura Mater Microvascular Network Weakening via a PDGF-BB-Dependent Mechanism." PloS one. 8: e82900.

        11.) Maier CL, Pober JS. (2011) "Human placental pericytes poorly stimulate and actively regulate allogeneic CD4 T cell responses." Arterioscler Thromb Vasc Biol. 31: 183-89.

        12.) Morozov A, Downey RJ, Healey J, Moreira AL, Lou E, Franceschino A, Dogan Y, Leung R, Edgar M, LaQuaglia M, Maki RG, Moore MA. (2010) "Benign mesenchymal stromal cells in human sarcomas." Clin Cancer Res. 16: 5630-40.

        13.) Stratman AN, Schwindt AE, Malotte KM, Davis GE. (2010) "Endothelial-derived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization." Blood. 116: 4720-30.

        14.) Xing C, Arai K, Park KP, Lo EH. (2010) "Induction of vascular endothelial growth factor and matrix metalloproteinase-9 via CD47 signaling in neurovascular cells." Neurochem Res 35: 1092-97.

        15.) Christian S, Winkler R, Helfrich I, Boos AM, Besemfelder E, Schadendorf D, Augustin HG. (2008) "Endosialin (Tem1) is a marker of tumor-associated myofibroblasts and tumor vessel-associated mural cells." Am J Pathol. 172: 486-94.

        16.) El-Bizri N, Guignabert C, Wang L, Cheng A, Stankunas K, Chang CP, Mishina Y, Rabinovitch M. (2008) "SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis." Development. 135: 2981-91.

        17.) El-Bizri N, Wang L, Merklinger SL, Guignabert C, Desai T, Urashima T, Sheikh AY, Knutsen RH, Mecham RP, Mishina Y, Rabinovitch M. (2008) "Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling." Circ Res. 102: 380-88.

        18.) Rouleau C, Curiel M, Weber W, Smale R, Kurtzberg L, Mascarello J, Berger C, Wallar G, Bagley R, Honma N, Hasegawa K, Ishida I, Kataoka S, Thurberg BL, Mehraein K, Horten B, Miller G, Teicher BA. (2008) "Endosialin protein expression and therapeutic target potential in human solid tumors: sarcoma versus carcinoma." Clin Cancer Res. 14: 7223-36.

        19.) Bagley RG, Weber W, Rouleau C, Teicher BA. (2005) "Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy." Cancer Res. 65: 9741-50.

        Question:

        Do you have an STR profile available for Human Brain Vascular Pericytes #1200?

        Answers:

        • Posted by Manoj Sharma on Thursday, April 21, 2016

          Hi Daniel,

          We apologize for the inconvenience, but the STR profile for Catalog #1200 is not currently available. Please email your request to TechSupport@sciencellonline.com and we will respond as soon as possible.”

          ?Best,

          Sciencell Team


        Question:

        Are they GFAP positive?

        Answers:

        • Posted by Manoj Sharma on Wednesday, April 20, 2016

          Hi duan,

          Human Brain Vascular Pericytes are NOT GFAP positive.

          Thank you

        Question:

        How are these cells isolated? Are they PDGFRb+? Do you know if they express other pericyte markers like NG2?

        Answers:

        • Posted by Karishma Shah on Tuesday, March 29, 2016

          Dear customer,

          Isolation method is proprietary. #1200 cells express both PDGF beta receptor and NG2.?

        Question:

        Do you know the ApoE genotype information of these human pericytes? ApoE2, ApoE3 or ApoE4. Can request a specific one?

        Answers:

        • Posted by Manoj Sharma on Thursday, January 7, 2016

          Hi,

          We do not test these. thanks for your interest, please email at techsupport@sciencellonline,.com for special services.

          SCIENCELL TEAM

        Question:

        The spec sheet says you can passage these cells 15 times, but I don't see it listed anywhere that they are immortalized. Please clarify.

        Answers:

        • Posted by Manoj Sharma on Thursday, January 7, 2016

          Hi Susan,

          The cells can proliferate for 15 population doublings, not 15 passages. Cells may reach 15 population doublings within 4-5 passages. thanks for your interest

          SCIENCELL


        相關產品
        貨號
        產品名稱
        規格
        價格
        指令
        聯系電話
        +86 10 63804220
        +86 10 63803739
        +86 10 63861816
        QQ客服
        99久久香蕉国产线看观看
        <dfn id="h3pb5"><noframes id="h3pb5">

          <output id="h3pb5"></output>

            <dfn id="h3pb5"><nobr id="h3pb5"><mark id="h3pb5"></mark></nobr></dfn>

            <listing id="h3pb5"><form id="h3pb5"></form></listing>