99久久香蕉国产线看观看

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      我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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      您當前所在位置:首 頁 > 產品展示 > 人類 > 腎臟細胞系統 人腎系膜細胞 HRMC

      人腎系膜細胞 HRMC

      英文名:Human Renal Mesangial Cells

      貨號:4200

      價格:$680

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      腎系膜細胞是血管周圍細胞,位于腎小球毛細血管袢之間的中央部位。系膜細胞有多種功能,包括合成和組裝的系膜基質,內吞作用和處理血漿大分子,通過系膜細胞收縮或血管活性激素的釋放[1]調控腎小球血流動力學。系膜細胞也能合成,聚集和控制腎小球系膜基質成分的變化。在多種腎小球疾病中,如IgA腎病、膜增生性腎小球腎炎、狼瘡性腎炎、腎小球硬化癥、糖尿病腎病等,均能檢測到腎小球系膜基質的生產過剩[2,3]。這些關鍵的作用表明腎系膜細胞是研究生理和病理環境下系膜損傷和腎小球功能的理想模型。
      Sciencell研究實驗室的人腎系膜細胞是從人的腎臟組織中分離得到的,純化后凍存,冰凍運輸。每管細胞密度超過5×10^5/ml。該細胞可通過纖連蛋白、Thy-1和平滑肌肌動蛋白特異性抗體的免疫熒光進行鑒定。本細胞經檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。如采用ScienCell 實驗室特制的培養基,可保證此細胞15倍增殖。

      推薦培養基:腎系膜細胞培養基 (MCM, Cat. #4201)
      貨號4200
      產地美國
      縮寫HRMC
      規格5 x 10^5/1ml
      用途科研
      儲存液氮
      運輸干冰
      1.) Ghada AK and J Golbahar. (2013) ?High Glucose-Induced Oxidative Stress Increases the Copy Number of Mitochondrial DNA in Human Mesangial Cells.??BioMed Research International. 2013: 1155-63?

      2.) Kang MK, Lim SS, Lee JY, Yeo KM, Kang YH. (2013) "Anthocyanin-Rich Purple Corn Extract Inhibit Diabetes-Associated Glomerular Angiogenesis."?PloS one. 8: e79823.

      3.) Li J, Lim SS, Lee ES, Gong JH, Shin D, Kang IJ, Kang YH. (2011) "Isoangustone A suppresses mesangial fibrosis and inflammation in human renal mesangial cells."Exp Biol Med (Maywood). 236: 435-44.

      4.) Wu F, Zhang W, Li L, Zheng F, Shao X, Zhou J, Li H. (2011) "Inhibitory effects of honokiol on lipopolysaccharide-induced cellular responses and signaling events in human renal mesangial cells."?Eur J Pharmacol. 654: 117-21.

      5.) Huang P, Zhang Y, Jiang T, Zeng W, Zhang N. (2010) "Role of aldose reductase in the high glucose induced expression of fibronectin in human mesangial cells."?Mol Biol Rep. 37: 3017-21.

      6.) Li J, Kang SW, Kim JL, Sung HY, Kwun IS, Kang YH. (2010) "Isoliquiritigenin entails blockade of TGF-beta1-SMAD signaling for retarding high glucose-induced mesangial matrix accumulation."?J Agric Food Chem. 58: 3205-12.

      7.) Jiang T, Qu JJ, Nishinaka T, Zhang N. (2008) "Transcription factor AP-1 regulates TGF-beta(1)-induced expression of aldose reductase in cultured human mesangial cells."?Nephrology (Carlton). 13: 212-7.

      8.) Mathew JT, Patni H, Chaudhary AN, Liang W, Gupta A, Chander PN, Ding G, Singhal PC. (2008) "Aldosterone induces mesangial cell apoptosis both in vivo and in vitro."Am J Physiol Renal Physiol. 295: F73-81.

      9.) Drel VR, Pacher P, Stevens MJ, Obrosova IG. (2006) "Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells."?Free Radic Biol Med. 40: 1454-65.?

      10.) Li Y, Wen X, Spataro BC, Hu K, Dai C, Liu Y. (2006) "Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferator-activated receptor-gamma agonists."?J Am Soc Nephrol. 17: 54-65.

      11.) Wen X, Li Y, Hu K, Dai C, Liu Y. (2005) "Hepatocyte growth factor receptor signaling mediates the anti-fibrotic action of 9-cis-retinoic acid in glomerular mesangial cells."Am J Pathol. 167: 947-57.

      12.) Dai C, Liu Y. (2004) "Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF."?J Am Soc Nephrol. 15: 1402-12.
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      99久久香蕉国产线看观看

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