99久久香蕉国产线看观看

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        我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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        人肝竇內皮細胞 HHSEC

        英文名:Human Hepatic Sinusoidal Endothelial Cells

        貨號:5000

        價格:$770

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        內皮細胞有很多生理功能,而且是許多病理進程的中心。肝臟包括兩種內皮細胞:血管內皮細胞和肝竇內皮細胞。肝竇內皮細胞是微血管內皮細胞有獨特的表型如同樹突和如同CD4+T細胞的獨特的抗原呈遞細胞的功能。因此SEC表現為一種新的組織存在形式,非專業的抗原呈遞細胞,其表現出與控制肝臟局部的免疫應答和免疫感應耐受性有關[1]。肝的微環境包括門靜脈成分和血竇細胞增殖而來的可溶性介質,通過SEC嚴格控制抗原呈遞來避免由免疫介導的損傷。SEC表達不同于大血管內皮細胞的特異性表面受體、有不同的形態和代謝[3]。研究表明SEC能夠動態調節細胞表面裂孔隙度,在肝臟再生時對局部環境的區域性刺激能夠快速的反應[2]。SEC功能紊亂和結構改變對整個肝臟有深遠的影響。
        Sciencell研究實驗室的臍靜脈內皮細胞是從人肝臟分離得到的,原代凍存,冰凍運輸。每管細胞密度超過5×10^6/ml。細胞特性經白蛋白、cytokeratin-18 and vimentin免疫熒光鑒定。本細胞經檢測不含HIV-1、HBV、HCV、支原體、細菌、酵母菌和真菌。HH不能擴大培養或者產期培養,因為它不能增殖。

        推薦培養基:內皮細胞培養基 (ECM, Cat. #1001)
        貨號5000
        產地美國
        縮寫HHSEC
        規格5 x 10^5 /1ml
        用途科研
        儲存液氮
        運輸干冰
        1.) Das A, Shergill U, Thakur L, Sinha S, Urrutia R, Mukhopadhyay D, Shah VH. (2013) "Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment."?Am J Physiol Gastrointest Liver Physiol. 298: G908-15

        2.) Lee SJ, Park SY, Jung MY, Bae SM, Kim IS. (2011) "Mechanism for phosphatidylserine-dependent erythrophagocytosis in mouse liver."?Blood. 117: 5215-23.

        3.) Das A, Shergill U, Thakur L, Sinha S, Urrutia R, Mukhopadhyay D, Shah VH. (2010) "Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment."?Am J Physiol Gastrointest Liver Physiol. 298: G908-15.?

        4.) Guilini C, Urayama K, Turkeri G, Dedeoglu DB, Kurose H, Messaddeq N, Nebigil CG. (2010) "Divergent roles of prokineticin receptors in the endothelial cells: angiogenesis and fenestration."?Am J Physiol Heart Circ Physiol. 298: H844-52.

        5.) Huebert RC, Vasdev MM, Shergill U, Das A, Huang BQ, Charlton MR, LaRusso NF, Shah VH. (2010) "Aquaporin-1 facilitates angiogenic invasion in the pathological neovasculature that accompanies cirrhosis."?Hepatology. 52: 238-48.

        6.) Kim Y, Larkin AL, Davis RM, Rajagopalan P. (2010) "The design of in vitro liver sinusoid mimics using chitosan-hyaluronic acid polyelectrolyte multilayers."?Tissue Eng Part A. 16: 2731-41.?

        7.) Tang L, Yang J, Liu W, Tang X, Chen J, Zhao D, Wang M, Xu F, Lu Y, Liu B, Sun Q, Zhang L, He F. (2009) "Liver sinusoidal endothelial cell lectin, LSECtin, negatively regulates hepatic T-cell immune response."?Gastroenterology. 137: 1498-508.e1-5.?

        8.) Jung MY, Park SY, Kim IS. (2007) "Stabilin-2 is involved in lymphocyte adhesion to the hepatic sinusoidal endothelium via the interaction with alphaMbeta2 integrin."?J Leukoc Biol. 82: 1156-65.

        9.) Nahmias Y, Casali M, Barbe L, Berthiaume F, Yarmush ML. (2006) "Liver endothelial cells promote LDL-R expression and the uptake of HCV-like particles in primary rat and human hepatocytes."?Hepatology. 43: 257-65.

        10.) Nahmias Y, Odde DJ. (2006) "Micropatterning of living cells by laser-guided direct writing: application to fabrication of hepatic-endothelial sinusoid-like structures."?Nat Protoc. 1: 2288-96.

        11.) Perri RE, Langer DA, Chatterjee S, Gibbons SJ, Gadgil J, Cao S, Farrugia G, Shah VH. (2006) "Defects in cGMP-PKG pathway contribute to impaired NO-dependent responses in hepatic stellate cells upon activation."?Am J Physiol Gastrointest Liver Physiol. 290: G535-42.
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        99久久香蕉国产线看观看

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