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      我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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      重組人成纖維細胞生長因子-19 rhFGF-19

      英文名:Recombinant Human Fibroblast Growth Factor-19

      貨號:104-19

      價格:$86

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      Fibroblast growth factor 19 (FGF-19) belongs to the large FGF family which has at least 23 members. However, FGF-19, along with FGF-21 and FGF-23, belongs to a subfamily of atypical FGFs where it lacks a conventional heparin-binding motif. Therefore, its signal transduction is mediated by the cofactor ?Klotho when interacting with FGFRs 1c, 2c and 3c. Interestingly, FGF-19 can interact directly with FGFR4 in absence of ?Klotho. FGF-19 regulates metabolic processes including bile acid, lipid and glucose homeostasis, as well as hepatocyte proliferation. Administration of recombinant FGF-19 to mice decreased cholesterol 7-alpha-hydroxylase (CYP7A1) expression, the rate limiting step in bile acid biosynthesis pathway in the liver.
      貨號104-19
      產地美國
      縮寫rhFGF-19
      規格5ug
      用途科研
      儲存-20度
      運輸干冰
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      99久久香蕉国产线看观看

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