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      我的購物車>> 中國區首家總代 專業十六載 打造細胞生物學精品
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      重組人腫瘤壞死因子-alpha Variant rhTNF-α variant

      英文名:Recombinant Human Tumor Necrosis Factor-alpha Variant

      貨號:103-01v

      價格:$86

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      The clinical use of the potent antitumor activity of TNF-α has been limited by the proinflammatory side effects including fever, dose-limiting hypotension, hepatotoxicity, intravascular thrombosis, and hemorrhage. Designing clinically applicable TNF-α mutants with low systemic toxicity has been an intense pharmacological interest. Human TNF-α, which binds to the murine TNF-α55 but not to the murine TNF-α75, exhibits retained antitumor activity and reduced systemic toxicity in mice compared with murine TNF-α, which binds to both murine TNF receptors. Based on these results, many TNF-α mutants that selectively bind to TNF-α55 have been designed. These mutants displayed cytotoxic activities on tumor cell lines in vitro, and exhibited lower systemic toxicity in vivo.
      貨號103-01v
      產地美國
      縮寫rhTNF-α variant
      規格10ug
      用途科研
      儲存-20度
      運輸干冰
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      99久久香蕉国产线看观看

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