平滑肌細胞是多數重要動脈疾病的靶細胞。血管SMC的生長潛力是原發血管病發展中至關重要的異常因素。最新研究表明SMC表達的鈣通道,其表面表達的ICAM-1和VCAM-1,均參與了血管壁的炎癥反應,并與血管疾病的進展和穩定有關。慢性肺組織缺氧能造成血管重塑,肺動脈平滑肌增生,最終導致肺動脈高壓。人血管平滑肌的體外培養可作為血管研究模型,為血管疾病的治療和藥理學研究提供信息,發揮重要作用。
人肺動脈平滑肌細胞提取于人肺動脈組織,二代凍存。每管含有細胞數>5×10^5 cells/ml,此細胞通過對alpha-SMA和Desmin免疫熒光染色驗證,經測試不含有HIV-1、HBV、HCV、支原體、細菌、酵母和真菌。細胞可以達到15倍增。
推薦培養基:平滑肌細胞培養基 (SMCM, Cat. #1101)
貨號 | 3110 |
產地 | 美國 |
縮寫 | HPASMC |
規格 | 5 x 10^5 /1ml |
用途 | 科研 |
儲存 | 液氮 |
運輸 | 干冰 |
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